Research
Advancing Biomedical Research at NUBRI
NUBRI Primary Research Goals
At NUBRI, our research is dedicated to advancing scientific understanding and improving public health through a multidisciplinary approach that combines genomics, molecular biology, and bioinformatics. Our primary research goals include; Applying cutting-edge techniques to reduce the burden of infectious diseases and enhance the public health infrastructure in Sudan. Each unit combines cutting-edge technologies, skilled personnel, and regional partnerships to drive innovation across key areas, including diagnostics, genomics, drug discovery, bioinformatics, and immunology. Together, these units foster a collaborative environment that bridges research, education, and real-world health solutions.
Ongoing Research & Active Projects
3
Seroprevalence and Molecular Characterization of Hepatitis D and B Viruses in Sudan
Status: Ongoing
Duration: 2024–2026
This ongoing research project aims to assess the seroprevalence and perform molecular characterization of Hepatitis D Virus (HDV) and Hepatitis B Viru...
Dr. Sofia Bashir Mohamed Ali
Hannover Medical School, Germany
Novel Insights into DOCK4 as a Tumor Suppressor and Biomarker in Lung Cancer: Comprehensive Bioinformatics Analysis of LUAD and LUSC
Status: Ongoing
This study investigates the Dedicator of Cytokinesis 4 (DOCK4) gene as a potential tumor suppressor and diagnostic biomarker in lung adenocarcinoma (L...
Dr. Sofia Bashir Mohamed Ali
Integrated In Silico Analysis of Antimicrobial Resistance Mechanisms in Sudanese Pseudomonas aeruginosa and Klebsiella pneumoniae
Status: Ongoing
Antimicrobial resistance (AMR) represents a growing global health threat, particularly in low- and middle-income countries such as Sudan. This project...
Dr. Sofia Bashir Mohamed Ali
Completed Research Projects
6
Uncovering Novel Resistance Mechanisms in Sudanese E. coli via In Silico Mutation Analysis of Key Drug Targets
Status: Completed
This project applies computational mutation analysis to investigate antimicrobial resistance mechanisms in Sudanese Escherichia coli isolates. By targ...
Dr. Sofia Bashir Mohamed Ali
Galaxy NUBRI: Democratizing Bioinformatics in Sudan
Status: Completed
Galaxy NUBRI is a locally hosted, user-friendly bioinformatics platform established by the National University Biomedical Research Institute (NUBRI) t...
Dr. Sofia Bashir Mohamed Ali
Green Synthesis of Silver Nanoparticles Using Sudanese Candida parapsilosis: A Sustainable Approach to Combat Antimicrobial Resistance
Status: Completed
Duration: 2023-2025
This research investigates the use of a native Sudanese isolate of Candida parapsilosis for the green biosynthesis of silver nanoparticles (AgNPs)....
Dr. Sofia Bashir Mohamed Ali
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Gram-Negative and Gram-Positive Bacteria Isolated from Sudan
Status: Completed
Duration: 2019–2024
This project aims to identify antimicrobial resistance (AMR) genes in clinically significant Gram-negative and Gram-positive bacterial strains isolate...
Dr. Sofia Bashir Mohamed Ali
Reverse Vaccinology and Immunoinformatics Approaches for Multi-Epitope Vaccine Design Against Klebsiella pneumoniae
Status: Completed
Duration: 2023–2025
This project employs reverse vaccinology and immunoinformatics approaches to develop a novel multi-epitope vaccine candidate against Klebsiella pneumo...
Dr. Sofia Bashir Mohamed Ali
The Impact of Mutations on TP53 Protein and MicroRNA Expression in HNSCC: Novel Insights for Diagnostic and Therapeutic Strategies
Status: Completed
This project investigates the structural and functional consequences of somatic mutations in the TP53 gene, a critical tumor suppressor, in Head and N...
Dr. Sofia Bashir Mohamed Ali